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Pyroluria is a term that describes abnormally high level of pyrroles, specifically hydroxyhemopyrrolin-2-one (HPL), which is a byproduct of hemoglobin synthesis. Pyrroles have a high affinity for certain key nutrients, notably vitamin B6 (pyridoxine) and zinc.

Pyrroles plus vitamin B6 and zinc, form complexes that are readily excreted in the urine. This leads to a depletion of these nutrients in the body because they are lost at a rate faster than they can be replenished by a regular diet.

Without adequate levels of these nutrients, a variety of symptoms may manifest, which are often attributed to pyroluria. Learn more about pyroluria here.

This page offers our most popular pyroluria supplements.



Best Copper Overload

AntiOxidant Formula 120 vegcaps


Most Popular Supplements for Pyroluria

GABA 90 caps 750mg


Best Copper Overload

Vitamin A 10000 IU 100 gels


Best Copper Overload

Zinc Picolinate 50mg